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Successful treatment of a recurrent granulation polyp in the airways with high-dose-rate brachytherapy: a case report

Polke, Markus ; Oelmann-Avendaño, Jan ; Warth, Arne ; Heussel, Claus-Peter ; Herth, Felix J. F. ; Eberhardt, Ralf

In: Journal of medical case reports, 11 (2017), Nr. 289. pp. 1-5. ISSN 1752-1947

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Download (873kB) | Lizenz: Creative Commons LizenzvertragSuccessful treatment of a recurrent granulation polyp in the airways with high-dose-rate brachytherapy: a case report by Polke, Markus ; Oelmann-Avendaño, Jan ; Warth, Arne ; Heussel, Claus-Peter ; Herth, Felix J. F. ; Eberhardt, Ralf underlies the terms of Creative Commons Attribution 3.0 Germany

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Abstract

Background Benign central airway tumors are very rare diseases. Their unspecific symptoms are responsible for late diagnosis. Endoscopic interventions with different techniques and tools are widely used for their treatment. However, in certain cases interventional endoscopy might be unsuccessful and therefore other methods such as high-dose-rate brachytherapy could be a therapeutic option. Case presentation A 76-year-old white German woman was referred to our clinic for an endoscopic treatment of a recurrent granulation polyp in her left main bronchus. She had dyspnea, coughing, and mucus retention. Three times resections via bronchoscopy were performed within less than a year. After each intervention the polyp regrew inside her left main bronchus causing a repeat of the initial symptoms. She presented to our clinic less than 1 month since the last intervention. Twice we performed a rigid bronchoscopy in total anesthesia where we resected the granulation polyp with a snare wire loop and did an argon plasma coagulation of its base. Due to the recurrent growing of the granuloma, we performed a high-dose-rate brachytherapy in conscious sedation after another interventional bronchoscopy with a resection of the polyp and argon plasma coagulation of the base. Three months after brachytherapy our patient came to our clinic for a follow-up with none of the initial symptoms. Only a small remnant of the polyp without a significant occlusion of her bronchus was visualized by bronchoscopy. Furthermore, 6 months after brachytherapy she was not presenting any of the initial symptoms. Conclusions This case report shows that high-dose-rate brachytherapy is a therapeutic option for the treatment of benign airway stenosis when other interventional treatments are not or are less than successful. However, further investigations are needed to prove the effectiveness and reliability of the method.

Item Type: Article
Journal or Publication Title: Journal of medical case reports
Volume: 11
Number: 289
Publisher: BioMed Central
Place of Publication: London
Date Deposited: 24 Oct 2017 08:32
Date: 2017
ISSN: 1752-1947
Page Range: pp. 1-5
Faculties / Institutes: Medizinische Fakultät Heidelberg > Medizinische Universitäts-Klinik und Poliklinik
Medizinische Fakultät Heidelberg > Radiologische Universitätsklinik
Medizinische Fakultät Heidelberg > Pathologisches Institut
Medizinische Fakultät Heidelberg > Thoraxklinik Heidelberg gGmbH
Subjects: 610 Medical sciences Medicine
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