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The art of nomograms

Mosquera, Samuel ; Ortueta, Diego ; Verma, Shwetabh

In: Eye and Vision, 5 (2018), Nr. 2. pp. 1-13. ISSN 2326-0254

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Abstract

Background: To retrospectively analyse strategies for adjusting refractive surgery plans with reference to the preoperative manifest refraction.

Methods: We constructed seven nomograms based on the refractive outcomes (sphere, cylinder, axis [SCA]) of 150 consecutive eyes treated with laser in situ keratomileusis for myopic astigmatism. We limited the initial data to the SCA of the manifest refraction. All nomograms were based on the strategy: if for x diopters (D) of attempted metric, y D is achieved; we can reverse this sentence and state for achieving y D of change in the metric, x D will be planned. The effects of the use of plus or minus astigmatism notation, spherical equivalent, sphere, principal meridians notation, cardinal and oblique astigmatism, and astigmatic axis were incorporated.

Results: All nomograms detected subtle differences in the spherical component (p < 0.0001). Nomograms 5 and 7 (using power vectors) and 6 (considering axis shifts) detected significant astigmatic differences (nomogram 5, p < 0.001; nomogram 6, p < 0.05; nomogram 7, p < 0.005 for cardinal astigmatism, p = 0.1 for oblique astigmatism). We observed mild clinically relevant differences (~ 0.5 D) in sphere or astigmatism among the nomograms; differences of ~ 0.25 D in the proposals for sphere or cylinder were not uncommon. All nomograms suggested minor improvements versus actual observed outcomes, with no clinically relevant differences among them.

Conclusions: All nomograms anticipated minor improvements versus actual observed outcomes without clinically relevant differences among them. The minimal uncertainties in determining the manifest refraction (~ 0.6 D) are the major limitation to improving the accuracy of refractive surgery nomograms.

Item Type: Article
Journal or Publication Title: Eye and Vision
Volume: 5
Number: 2
Publisher: BioMed Central
Place of Publication: London
Date Deposited: 27 Apr 2018 14:02
Date: 2018
ISSN: 2326-0254
Page Range: pp. 1-13
Faculties / Institutes: Service facilities > Interdisciplinary Center for Scientific Computing
Service facilities > Institut f. Technische Informatik (ZITI)
Medizinische Fakultät Heidelberg > Radiologische Universitätsklinik
Subjects: 570 Life sciences
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