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Corneal functional optical zone under monocular and binocular assessment

Mosquera, Samuel Arba ; de Ortueta, Diego ; Verma, Shwetabh

In: Eye and Vision, 5 (2018), Nr. 3. pp. 1-13. ISSN 2326-0254

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Background: In this retrospective randomized case series, we compared bilateral symmetry between OD and OS eyes, intercorneal differences and Functional Optical Zone (FOZ) of the corneal aberrations.

Methods: Sixty-seven normal subjects (with no ocular pathology) who never had any ocular surgery were bilaterally evaluated at Augenzentrum Recklinghausen (Germany). In all cases, standard examinations and corneal wavefront topography (OPTIKON Scout) were performed. The OD/OS bilateral symmetry was evaluated for corneal wavefront aberrations, and FOZ-values were evaluated from the Root-Mean-Square (RMS) of High-Order Wavefront-Aberration (HOWAb). Moreover, correlations of FOZ, spherical equivalent (SE), astigmatism power, and cardinal and oblique astigmatism for binocular vs. monocular, and binocular vs. intercorneal differences were analyzed.

Results: Mean FOZ was 6.56 ± 1.13 mm monocularly, 6.97 ± 1.34 mm binocularly, and 7.64 ± 1.30 mm intercorneal difference, with all strongly positively correlated, showing that the diameter of glare-free vision is larger in binocular than monocular conditions. Mean SE was 0.78 ± 1.30 D, and the mean astigmatism power (magnitude) was 0.46 ± 0.52 D binocularly. The corresponding monocular values for these metrics were 0.78 ± 1.30 D and 0.53 ± 0.53 D respectively. SE, astigmatism magnitude, cardinal astigmatism component, and FOZ showed a strong correlation and even symmetry; and oblique astigmatism component showed odd symmetry indicating Enantiomorphism between the left and right eye.

Conclusions: These results confirm OD-vs.-OS bilateral symmetry (which influences binocular summation) of HOWAb, FOZ, defocus, astigmatism power, and cardinal and oblique astigmatism. Binocular Functional Optical Zone calculated from corneal wavefront aberrations can be used to optimize refractive surgery design.

Item Type: Article
Journal or Publication Title: Eye and Vision
Volume: 5
Number: 3
Publisher: BioMed Central
Place of Publication: London
Date Deposited: 02 May 2018 09:11
Date: 2018
ISSN: 2326-0254
Page Range: pp. 1-13
Faculties / Institutes: Service facilities > Interdisciplinary Center for Scientific Computing
Service facilities > Institut f. Technische Informatik (ZITI)
Medizinische Fakultät Heidelberg > Radiologische Universitätsklinik
Subjects: 610 Medical sciences Medicine
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