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PSMA-PET based radiotherapy: a review of initial experiences, survey on current practice and future perspectives

Zschaeck, Sebastian ; Lohaus, Fabian ; Beck, Marcus ; Habl, Gregor ; Kroeze, Stephanie ; Zamboglou, Constantinos ; Koerber, Stefan Alexander ; Debus, Jürgen ; Hölscher, Tobias ; Wust, Peter ; Ganswindt, Ute ; Baur, Alexander D. J. ; Zöphel, Klaus ; Cihoric, Nikola ; Guckenberger, Matthias ; Combs, Stephanie E. ; Grosu, Anca Ligia ; Ghadjar, Pirus ; Belka, Claus

In: Radiation Oncology, 13 (2018), Nr. 90. pp. 1-9. ISSN 1748-717X

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Download (746kB) | Lizenz: Creative Commons LizenzvertragPSMA-PET based radiotherapy: a review of initial experiences, survey on current practice and future perspectives by Zschaeck, Sebastian ; Lohaus, Fabian ; Beck, Marcus ; Habl, Gregor ; Kroeze, Stephanie ; Zamboglou, Constantinos ; Koerber, Stefan Alexander ; Debus, Jürgen ; Hölscher, Tobias ; Wust, Peter ; Ganswindt, Ute ; Baur, Alexander D. J. ; Zöphel, Klaus ; Cihoric, Nikola ; Guckenberger, Matthias ; Combs, Stephanie E. ; Grosu, Anca Ligia ; Ghadjar, Pirus ; Belka, Claus underlies the terms of Creative Commons Attribution 4.0

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Abstract

Gallium prostate specific membrane antigen (PSMA) ligand positron emission tomography (PET) is an increasingly used imaging modality in prostate cancer, especially in cases of tumor recurrence after curative intended therapy. Owed to the novelty of the PSMA-targeting tracers, clinical evidence on the value of PSMA-PET is moderate but rapidly increasing. State of the art imaging is pivotal for radiotherapy treatment planning as it may affect dose prescription, target delineation and use of concomitant therapy. This review summarizes the evidence on PSMA-PET imaging from a radiation oncologist’s point of view. Additionally a short survey containing twelve examples of patients and 6 additional questions was performed in seven mayor academic centers with experience in PSMA ligand imaging and the findings are reported here.

Item Type: Article
Journal or Publication Title: Radiation Oncology
Volume: 13
Number: 90
Publisher: BioMed Central
Place of Publication: London
Date Deposited: 01 Jun 2018 09:26
Date: 2018
ISSN: 1748-717X
Page Range: pp. 1-9
Faculties / Institutes: Service facilities > German Cancer Research Center (DKFZ)
Medizinische Fakultät Heidelberg > Radiologische Universitätsklinik
Subjects: 610 Medical sciences Medicine
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