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Development of highly integrated PET/MR detector modules

Sacco, Ilaria

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Abstract

In the last 20 years, PET imaging has become a very valuable technique for clinical diagnosis. It gives functional information on glucose metabolism and cancerous cell growth and, if coupled with precise anatomical information from MRT scans, can lead to very accurate results. The aim of the present work is the design of highly performing PET detector modules, to be used for both clinical and pre-clinical applications and compatible with operations inside MR scanner. A single-layer ceramic module, hosting both sensors and readout electronics, efficiently thermally decoupled thanks to an integrated liquid cooling channel, has been designed, fabricated and tested. Novel single-ended front-end architecture, studied for low input impedance and good timing resolution, has been designed and integrated on PETA ASIC for SiPM readout. SiPM dies for maximum light collection and identification of sub-millimeter scintillating crystals have been designed and characterized. The assembly is very compact, with an area of 32mm x 32mm, about 8mm thick without crystals, with up to 144 readout channels. It has proved excellent ToF resolution of about 230 ps CRT at FWHM for detectors in coincidence. The same module has been able to identify sub-millimeter scintillating crystals.

Item Type: Dissertation
Supervisor: Fischer, Prof. Dr. Peter
Date of thesis defense: 9 November 2016
Date Deposited: 28 Nov 2016 07:31
Date: 2016
Faculties / Institutes: The Faculty of Physics and Astronomy > Dekanat der Fakultät für Physik und Astronomie
Subjects: 530 Physics
600 Technology (Applied sciences)
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