Directly to content
  1. Publishing |
  2. Search |
  3. Browse |
  4. Recent items rss |
  5. Open Access |
  6. Jur. Issues |
  7. DeutschClear Cookie - decide language by browser settings

Coherence-Gated Wave-Front Sensing in Strongly Scattering Samples

Feierabend, Marcus

German Title: Kohärenzgatter-Wellenfrontabtastung in stark streuenden Proben

[thumbnail of MarcusFeierabendPhDThesis.pdf]
PDF, English
Download (23MB) | Terms of use

Citation of documents: Please do not cite the URL that is displayed in your browser location input, instead use the DOI, URN or the persistent URL below, as we can guarantee their long-time accessibility.


In this thesis coherence-gated wave-front sensing (CGWS), a new approach for measuring wave-fronts in strongly scattering samples, is presented. This method combines Shack-Hartmann wave-front sensing and phase shifting interferometry (PSI). It employs virtual lenses to mimic the function of a conventional Shack-Hartmann sensor. The use of a modal estimation algorithm allows an approximation of the measured wave-front with a linear combination of Zernike polynomials up to the fifth radial degree. The principle of CGWS is tested by measuring two wave-front aberrations, defocus and astigmatism, for a mirror as a sample and a strongly scattering sample. The results are compared to theoretical models. The main advantage of CGWS is the discrimination against light backscattered from outside the focal region. A further advantage is the increase in the effective detection sensitivity. The capabilities of CGWS are demonstrated with wave-front measurements in scattering samples in the presence of background light that is dominant by about three orders of magnitude. In various microscopy applications, the ability to pre-emptively correct the wave-front, employing CGWS measurement data, may allow improvements of the optical focus and thus enhance the resolution and depth penetration in tissue considerably.

Document type: Dissertation
Supervisor: Denk, Prof. Dr. Winfried
Date of thesis defense: 30 June 2004
Date Deposited: 17 Aug 2004 10:27
Date: 2004
Faculties / Institutes: Service facilities > Max-Planck-Institute allgemein > MPI for Medical Research
DDC-classification: 530 Physics
Controlled Keywords: Adaptive Optik, Wellenfront, Wellenfrontsensor, Optische Kohärenz, Fluoreszenzmikroskopie
Uncontrolled Keywords: Optische KohärenztomographieAdaptive Optics , Wave-Front Sensing , Coherence , Optical Coherence Tomography , Fluorescence Microscopy
About | FAQ | Contact | Imprint |
OA-LogoDINI certificate 2013Logo der Open-Archives-Initiative