A

Argos Vélez, Paula (2024) Angiocrine factors in hepatocellular carcinoma: Modelling hepatocarcinogenesis to investigate Wnt signaling. [Dissertation]

Athanasiou, Christina (2024) Modeling of mechanistic effects of neurotrophin modulators. [Dissertation]

Aviles Huerta, Daniela (2024) Dual Ribosome Profiling uncovers metabolic vulnerabilities in the Tumor Microenvironment of Triple Negative Breast Cancer. [Dissertation]

Ayuso Jimeno, Irene Pilar (2024) Role of dorsal periaqueductal grey in instinctive defensive behavior. [Dissertation]

B

Basu, Soham (2024) The roles of basement membrane during larva-polyp morphogenesis of the starlet sea anemone Nematostella vectensis. [Dissertation]

Benedetto, Sarah (2024) Evolutionary dynamics of oligodendrogliomas. [Dissertation]

Berger, Aileen (2024) NY-BR-1 specific CAR+ T cells engineered by S/MAR vectors prove effectiveness in pre-clinical models of breast cancer. [Dissertation]

Bergheim, Bruno Gideon (2024) Molecular Atlas and Developmental Dynamics of the Nematostella vectensis Mesoglea. [Dissertation]

Bergler, Frederik (2024) Impact of FATP4 upregulation and related parameters on trans-endothelial fatty acid transport. [Dissertation]

Berschneider, Karina (2024) Functional and molecular characterization of the effects of Arnica montana L. extracts and corresponding lead compounds on primary human T cells. [Dissertation]

Blanco Carmona, Enrique (2024) Characterizing tumor heterogeneity in ATRT and IDH-mutant glioma tumors using single-cell multi-omics analyses. [Dissertation]

Boiti, Alessandra (2024) Decoding Transcriptional Regulation in Response to Sunlight in Vertebrates. [Dissertation]

Bortecen, Toman Deniz (2024) Analyzing the individual contributions of translation initiation factors to shaping the proteome of cancer cells. [Dissertation]

Böhler, Anna (2024) Structure of the microtubule nucleation sites. [Dissertation]

C

Capraz, Klemens Tümay (2024) Dimensionality reduction methods for high-dimensional biological data analysis. [Dissertation]

Carvajal Ibanez, Damian (2024) Interferon modulates adult neurogenesis by regulating mRNA translation and cell cycle in neural stem cells. [Dissertation]

Cavka, Ivana (2024) Investigating the timing of crossover designation in Caenorhabditis elegans meiosis. [Dissertation]

Chih, Yu-Chan (2024) Development of MHC-dependent immunotherapy for gliomas. [Dissertation]

Chocarro Pérez de Azanza, Sara (2024) Cell of origin and fusion variants of Eml4-Alk in non-small cell lung cancer. [Dissertation]

Colasanti, Ombretta (2024) Exploring innate immune induction and interference mechanisms of Hepatitis A and C Viruses in human hepatocytes: a comparative analysis. [Dissertation]

Criado Moronati, Elvira Magdalena (2024) Characterization of tumor-infiltrating CD8+ T cells towards clinical application. [Dissertation]

D

Da Cruz Vieira, Jose Ricardo (2024) Neurovascular interactions in the spinal cord during embryonic development and pathology. [Dissertation]

Dalal, Vineet (2024) Distinct roles for Polycomb repressive complexes in synovial sarcoma. [Dissertation]

Daugėlaitė, Klaudija (2024) Regulation of hormonal stimulation and ageing in female reproductive tract. [Dissertation]

Deschamps, Joran (2024) Towards quantitative high-throughput 3D localization microscopy. [Dissertation]

Dimitrov, Daniel (2024) Modelling Cell-cell Communication using Prior Knowledge with Single-cell and Spatially-resolved Omics Data. [Dissertation]

Dolejs, Vojtech (2024) Protein-RNA interactions in centromeric chromatin. [Dissertation]

Domínguez Azorín, Daniel (2024) Imaging-based drug development targeting tumor microtube networks in glioblastoma. [Dissertation]

Dos Santos, José Carlos (2024) Development of inhibitors of the prostate specific membrane antigen (PSMA) for imaging and endoradiotherapy. [Dissertation]

F

Fan, Pengfei (2024) The roles of two TIFY proteins in the regulation of the shoot apical meristem in Arabidopsis thaliana. [Dissertation]

Fernández Vaquero, Mirian Concepción (2024) Deciphering the role of mutant-IDH1 in liver cancer development and the tumor immune microenvironment. [Dissertation]

Fiorentino, Federica (2024) Structural and biochemical analysis of the human Rea1-Rsa4 pre-ribosomal complex enables the identification of small molecule inhibitors that impair human cancer cell growth. [Dissertation]

Fischer, Sabeth Maria Sheela (2024) Impact of neurotoxic substances on the development and behavior of zebrafish embryos Case studies with nicotine, desnitro-imidacloprid and three antidepressants. [Dissertation]

Fitzgerald, Donnacha (2024) Tumor Evolution through Differentiation in B-Cell Lymphomas. [Dissertation]

Flad, Sophia (2024) tRNA modification landscape shaping protein synthesis and energy production in early ectodermal differentiation. [Dissertation]

Focaccia, Enrico (2024) Exploring the effects of different FXR agonists on progression of Non-Alcoholic Steatohepatitis and its transition to Hepatocellular Carcinoma. [Dissertation]

Folkard, Ross (2024) Primary Somatosensory Cortical Outputs Bidirectionally Modulate Nociceptive Perception, Cortical Excitability, and Thalamic Firing Mode. [Dissertation]

Formichetti, Sara (2024) The role of a nuclear glycosylation in the early mammalian embryo. [Dissertation]

Frank, Simon (2024) Long Acting Injectable Formulations of Biologicals: Examination of an innovative polymer family for the controlled release of peptides and proteins. [Dissertation]

Förster, Jonas Dieter (2024) Mass spectrometry-based identification of HPV16 target epitopes for therapeutic vaccine design. [Dissertation]

Förster, Leo Carl (2024) Tumor Pseudolineages from a Healthy Lineage Template Reveal Organizational Principles and Cell-Fate Modulators in Glioblastoma. [Dissertation]

G

Ganjian, Noujan (2024) Identification of a plasticity driver of Combined Hepatocellular-Cholangiocarcinoma using functional interspecies comparison. [Dissertation]

Garcia Cortizo, Fabiola Helena (2024) Regulation of Glo1 activity via tyrosine phosphorylation and the impact of methylglyoxal on cellular metabolism. [Dissertation]

Garcés Lázaro, Irene (2024) Restoring NK cells function against cancer. [Dissertation]

George, Nikhil Oommen (2024) Dysregulation of alternative polyadenylation in autism spectrum disorders and its potential use in ASD diagnosis. [Dissertation]

Giebel, Nicole Yue Ling (2024) Regulation of Wnt signalling by the deubiquitinase USP42 in adult stem cells and colorectal cancer. [Dissertation]

Girbig, Mathias (2024) Structural analysis of human and yeast RNA polymerase III. [Dissertation]

Gnouamozi, Gnimah Eva (2024) Characterization of hepatitis delta virus-like agents: Insights into evolution, replication dynamics, and host interactions. [Dissertation]

Gopisetty, Apurva (2024) ITCC-P4: Molecular characterization and multi-omics analysis of pediatric patient tumor and Patient-Derived Xenograft (PDX) models for preclinical model selection. [Dissertation]

Gordillo Perez, Lucia (2024) Characterization of BDNF-dependent chromatin responses and adaptations in postmitotic neurons. [Dissertation]

Grein, Steve (2024) Stress induced lncRNA Lockd inhibits proliferation and angiogenesis of myocardial endothelial cells and promotes maladaptive cardiac remodelling during pressure overload. [Dissertation]

Großmann, Josina (2024) The regulation of polo-like kinase 4 in centrosome duplication. [Dissertation]

Gómez, Guillermo Martín (2024) Mechanisms of chloroquine resistance in Plasmodium falciparum. [Dissertation]

H

Haghani, Sara (2024) Characterization of the regulatory role of cysteine synthase complex in Arabidopsis thaliana. [Dissertation]

Hai, Ling (2024) Characterization of tumor subpopulations in glioblastoma with single cell transcriptomics. [Dissertation]

Hammer, Annika ; Hesse, Armen ; Reents, Frederike ; Strohmaier, Paul ; Schneider-Vielsäcker, Frederike ; Tretakov, Alexandra (2024) Literaturwissenschaften. [Book Section]

Heber, Nora Heike (2024) The Impact of Cycling Hypoxia on the Phenotype of HPV-Positive Cervical Cancer Cells. [Dissertation]

Heinzelmann, Elisa (2024) The role of MYT1L in brain tumor formation, progression and plasticity. [Dissertation]

Hellweg, Lars (2024) Development of Chemogenetic Biosensors with Large Dynamic Ranges and Spectral Flexibility. [Dissertation]

Hemanna, Shruthi (2024) Targeting EEF1A in fibroblasts to counteract cardiac fibrosis. [Dissertation]

Hering, Marvin (2024) Sptlc2-derived sphinganine is indispensable for inflammatory TLR4 signaling in macrophages. [Dissertation]

Hermann, Julia (2024) The interplay between mTORC1 and tRNA wobble modification in generating the protein synthesis machinery. [Dissertation]

Herter, Sonja Ildiko (2024) Multi-Parametric Drug Screening identifies Vulnerabilities and Combination Treatment Strategies for Neuroblastoma Subtypes. [Dissertation]

Hervas Sotomayor, Francisca (2024) Tracing the origins and evolution of the vertebrate brain: a comparative cellular study in anamniotes. [Dissertation]

Ho, Kim Hoa (2024) The development and tumorigenesis of choroid plexus. [Dissertation]

Hoffmann, Johannes Gerold (2024) Der Einfluss einer pathologisch veränderten vaskulärer Nische auf die Lebermetastasierung des malignen Melanoms. [Dissertation]

Hofman, Tomáš (2024) Defining innate immune checkpoints controlling Natural Killer cell recognition of melanoma cells. [Dissertation]

Hong, Yuhang (2024) Evolution and regulation of the transcriptional response to oxidative stress in vertebrates. [Dissertation]

Häfele, Verena (2024) Liver-specific endothelial mechanisms of melanoma metastasis. [Dissertation]

Hübenthal, Anna (2024) Influence of antimicrobial compounds and the RNA-binding protein RibR on the activity of B vitamin-responsive bacterial riboswitches. [Dissertation]

I

itani, Abdul Rahman (2024) Stress Signaling Heterogeneity in Normal and Malignant Hematopoiesis. [Dissertation]

J

Jakab, Moritz (2024) Vascular control of metastatic tumor cell fates. [Dissertation]

Janzen, Jakob (2024) Analysis of High-mobility Group A proteins in nonalcoholic steatohepatitis (NASH) and liver cancer. [Dissertation]

Jenseit, Anne Lena (2024) Developing targeted therapies for pediatric PFA ependymoma. [Dissertation]

K

Kanngießer, Sibylle (2024) Regulation of the ubiquitin ligase Ubr1 by the intrinsically disordered protein Roq1. [Dissertation]

Kasakovski, Dimitri (2024) Endothelial Smad6 and Smad7 harmonize blood vessel development and tumor progression. [Dissertation]

Kavishwar, Gayatri (2024) Boosting the Immune System: A Drug Combination Augments H-1 Parvovirus Mediated Oncolysis and Immunogenicity in Prostate Cancer. [Dissertation]

Kehrer, Jessica (2024) Identification and functional characterization of micronemal proteins in Plasmodium berghei parasites. [Dissertation]

Kelekçi, Simge (2024) Epigenetic compound screening in AML with MNX1 overexpression. [Dissertation]

Kellermann, Laura (2024) World hunger versus biodiversity: transformation approaches towards a sustainable agricultural system. [Dissertation]

Kocher, Daniela (2024) Exploring molecular mechanisms involved in tumor rebound growth after MAPKi withdrawal in pLGG. [Dissertation]

Kreis, Julian (2024) Enhancing Cancer Diagnostics Through Quality-Focused Gene Expression Signature Analyses. [Dissertation]

L

Lam, Wai Ling Macrina (2024) The Receptor for Advanced Glycation End Products (RAGE) controls ductular reaction-mediated fibrosis during cholestasis. [Dissertation]

Lasser, Samantha (2024) MDSC activation mediated by extracellular vesicles-associated microRNA in melanoma. [Dissertation]

Lecomte, Léa Candice Lucie (2024) Structural Studies of DNA-bound Condensin. [Dissertation]

Leppä, Aino-Maija (2024) Characterization of the molecular heterogeneity in acute myeloid leukemia for effective targeting of disease-driving leukemic stem cells. [Dissertation]

Li, Tengfeng (2024) Identification of RBM39 as a key regulator of innate immune response, governing basal expression of IRF3 and other critical pathway components. [Dissertation]

Liu, Xiaomin (2024) Analysis of cell division plane orientation in cambium stem cells. [Dissertation]

Lázaro Farré, Jorge (2024) The regulation and scaling of developmental tempo across mammalian species. [Dissertation]

M

Madenach, Lukas (2024) Computational multi-omics analysis of pediatric DADDR patients and synthetic lethality prediction in K27M mutated pediatric high-grade glioma. [Dissertation]

Madi, Alaa Abdelghani Mohamed (2024) Development and homeostasis of memory CD8+ T cells and implications for cancer immunotherapy. [Dissertation]

Malovrh, Ellen (2024) Translated small open reading frames shape the cardiac response to injury. [Dissertation]

Man, Ka-Hou (2024) Roles of SOX10 in Glioblastoma Stem Cell Plasticity. [Dissertation]

Max, Frank (2024) Modeling epigenetic heterogeneity across time and genome in single-cell multi-omics experiments. [Dissertation]

Mieg, Alessa (2024) Aging- and obesity-associated metabolic reprogramming suppresses CD8+ T cell responses. [Dissertation]

Mocaer, Karel (2024) Ultrastructural characterization of dinoflagellates from heterogeneous marine environmental samples. [Dissertation]

Moghe, Prachiti (2024) Cellular mechanisms underlying tissue pattern emergence in the developing embryo. [Dissertation]

Munoz Perez-Vico, Elena (2024) Implications of the Val66Met polymorphism of the BDNF gene on neuronal morphology and function using human iPSC-derived neuronal cultures. [Dissertation]

N

Narr, Andreas (2024) Classification of acute myeloid leukemia as a ferroptosis-sensitive malignancy suggesting the development of arsenic trioxide mediated ferroptosis-inducing combination therapies. [Dissertation]

Nees, Timo Albert (2024) The molecular mechanism and physiological role of silent nociceptor activation. [Dissertation]

Noble, Michelle (2024) Mitochondrial metabolic enzymes as RNA Binding Proteins: Exploring the RNA binding landscape of MDH2 and ATP5A1. [Dissertation]

O

Oludada, Opeyemi Ernest (2024) Characterization of human antibodies against Plasmodium falciparum circumsporozoite protein (PfCSP) epitopes. [Dissertation]

Onistschenko, Jasmin (2024) Stem cell homeostasis in medaka neuromasts – Keratin 15 as a regulator of proliferation. [Dissertation]

P

Pavlovic, Bojana (2024) Investigating the role of Rab GTPases in Wnt secretion in Drosophila melanogaster. [Dissertation]

Peters, Niklas (2024) Regulation of the ubiquitin ligase Ubr1 during protein quality control. [Dissertation]

Peterson, Julia (2024) Developments Toward an iPSC-Derived T-Cell Immunotherapy Using S/MAR DNA Vectors: A Focus on Hematopoietic Stem and Progenitor Cells. [Dissertation]

Pidelaserra Martí, Gemma (2024) Exploring the Interplay of Oncolytic Measles Vaccines with the Cancer-Immunity Cycle. [Dissertation]

Pirmann, Sebastian (2024) Pharmacogenomic Analyses of Next-Generation Sequencing Data from Cancer Patients. [Dissertation]

Poelchen, Juliane (2024) Generation of melanoma antigen-specific CD8+ T cells from human induced pluripotent stem cells for adoptive cell therapy. [Dissertation]

Pożoga, Marlena (2024) Understanding the stress-induced regulation of Nα-terminal acetylation and its function in the control of proteostasis in Arabidopsis thaliana. [Dissertation]

Puranachot, Pitithat (2024) Next-Generation Sequencing Analysis of Cell-Free DNA Identifies Actionable Alterations and Genomic Features in Pediatric Cancers. [Dissertation]

Q

Quirós Fernández, Isaac (2024) Novel T cell receptors reactive to the HPV16 E6 and E7 oncoproteins and strategy to potentiate their signaling strength using a co-stimulatory chimeric antigen receptor. [Dissertation]

R

Rada, Jona (2024) The link between glycolysis and signaling during mouse embryo segmentation. [Dissertation]

Ravichandran-Schmidt, Pirathitha (2024) Computational Modeling of Time perception and its Dopaminergic Modulation. [Dissertation]

Rehder, Klara Franziska (2024) Deciphering the role of heterozygous 3q28 deletion in the pathogenesis of schizophrenia in iPSC-derived human cortical neurons. [Dissertation]

Ren, Yonggang (2024) Studies of Jmjd6 in embryogenesis and ISL1 phosphorylation in cardiac development. [Dissertation]

Rheinberger, Mona (2024) Characterization of the HIV-1 integration site landscape and chromatin determinants of integration in microglia cellular models and CD4+ T cells. [Dissertation]

Roiuk, Mykola (2024) New insights into non-canonical modes of mRNA translation. [Dissertation]

Rucli, Sofia (2024) Functional study of O-GlcNAc modification of chromatin associated proteins. [Dissertation]

Ruperti, Fabian (2024) The evolution of cellular functional modules and the origin of coordinated behavior in Metazoa. [Dissertation]

Röhrich, Rachel Maria (2024) The V-ATPase at the trans-Golgi network/early endosome during vegetative and reproductive development. [Dissertation]

S

Saftien, Aurelia Dorothea (2024) Investigating Fungi- Mammalian Host Interactions in Health and Disease Using Organoids and Mouse Models. [Dissertation]

Sandmann, Christoph (2024) Translational Control of an Inflammatory Network in the Heart. [Dissertation]

Schmidt, Malin (2024) The psychedelic psilocin fosters neuroplasticity in iPSC-derived human cortical neurons. [Dissertation]

Schnell, Anna-Clara (2024) Virus Venetian Masked Ball: Does the Hepatitis Delta Virus Use Different Helper Viruses? [Dissertation]

Schwerd-Kleine, Paul Albert Wolfgang (2024) Dissecting the Cellular and Molecular Landscape of Inflammatory Breast Cancer through Single-Cell and Spatial Transcriptomics. [Dissertation]

Schwickert, Jonas Norbert (2024) Characterization of PARP inhibitor resistance in patient-derived ovarian cancer cell lines. [Dissertation]

Seifert Davila, Wolfram Heinrich (2024) Structural and functional studies of human and yeast transcription factor IIIC (TFIIIC). [Dissertation]

Simoes Costa, Ana Luisa (2024) Computational approaches to the study of chromatin in disease: examples from cancer and infection. [Dissertation]

Sokolova, Natalia (2024) From progenitors to stem cells: emergence and characterization of adult retinal stem cells in medaka. [Dissertation]

Sollier, Etienne (2024) Enhancer hijacking in acute myeloid leukemia with a complex karyotype. [Dissertation]

Staniczek, Theresa (2024) Endothelial regulation of liver homeostasis and regeneration. [Dissertation]

Starostecka, Maja Dorota (2024) Characterization of cell-type-specific responses to doxorubicin treatment in murine breast cancer organoids using a single-cell multi-omics approach. [Dissertation]

Steimbach, Raphael René (2024) SELECTIVE INHIBITORS AND TARGETED DEGRADERS OF HISTONE DEACETYLASE 10. [Dissertation]

Steinhauer, Michelle (2024) Development of a novel human co-culture model to study interactions between intestinal immune and epithelial cells. [Dissertation]

T

Tauch, Saskia (2024) Communication between fibroblasts and tumour cells in the tumour microenvironment during melanoma progression. [Dissertation]

Theile, Laura (2024) Cell type-dependent functions of centrosome linker components and their role in centrosome clustering and mitotic spindle formation. [Dissertation]

Thiel, Vera (2024) Analysis of neuronal infiltration in healthy pancreas and pancreatic ductal adenocarcinoma. [Dissertation]

Tollervey, Fergus (2024) Architecture of C. elegans centrosomes as revealed by cryo-electron tomography. [Dissertation]

Tolou Dabbaghian, Bahardokht (2024) Use of pharmaceutical and transgenic interventions in dissection of neuropathic pain mechanisms in spinal cord injury. [Dissertation]

Trovato, Matteo (2024) The role of histone H3.3 K9 and K27 residues in transcriptional regulation in mouse embryonic stem cells. [Dissertation]

Tüchler, Nadine (2024) Dynamic multi-omics and mechanistic modeling of kidney fibrosis progression. [Dissertation]

V

Vaßholz, Corinna (2024) Auswirkungen von Bacillus thuringiensis israelensis auf die Dipterenzönose im Auwald mit einem Schwerpunkt auf der Familie der Chironomidae. [Dissertation]

Vieira Codeco Marques, Luisa (2024) Identification of small molecules and miRNA inducing M1-like polarisation of murine and human macrophages. [Dissertation]

W

Wangemann, Julia (2024) A human iPSC-based model for synaptic pruning-associated changes in schizophrenia. [Dissertation]

Wassmer, Elsa (2024) What makes an RNA-binding protein (RBP): exploring the RNA-binding domains (RBDs) of experimentally detected RBPs. [Dissertation]

Wilhelm, Jonas (2024) Engineering of a Split Self-Labeling Protein for Recording Neuronal Activity and Connectivity. [Dissertation]

Würtz, Martin (2024) Integrative structural biology of recombinant γ-tubulin-related complexes. [Dissertation]

Y

Yserentant, Klaus (2024) Tools for quantitative Fluorescence Microscopy on the Nanoscale. [Dissertation]

Yuan, Zhao (2024) Analysis of somatic copy number alterations in liquid biopsies from cancer patients. [Dissertation]

Ç

Çelikyürekli, Simay (2024) Specific Combination Therapy for H3K27M Pediatric Diffuse Midline Glioma. [Dissertation]

Š

Švambarytė, Silvija (2024) Integration of axis elongation and somite patterning via signaling dynamics in the medaka embryo. [Dissertation]